{"id":84158,"date":"2023-08-10T20:15:05","date_gmt":"2023-08-10T20:15:05","guid":{"rendered":"https:\/\/msdconecta.co.cr\/es\/?post_type=product&#038;p=84158"},"modified":"2024-10-31T15:53:13","modified_gmt":"2024-10-31T15:53:13","slug":"bridion-wp-0695","status":"publish","type":"product","link":"https:\/\/msdconecta.co.cr\/es\/products\/bridion-wp-0695\/","title":{"rendered":"Bridion"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/bridion-info-banner.png?w=811\" alt=\"\" class=\"wp-image-84159\" width=\"1313\" height=\"436\" srcset=\"https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/bridion-info-banner.png 811w, https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/bridion-info-banner.png?resize=300,100 300w, https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/bridion-info-banner.png?resize=768,256 768w, https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/bridion-info-banner.png?resize=320,107 320w, https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/bridion-info-banner.png?resize=120,40 120w\" sizes=\"auto, (max-width: 1313px) 100vw, 1313px\" \/><\/figure>\n\n\n\n<p class=\"has-object-object-font-size mhh-mcn-v1-paragraph--center  mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--994c4189770a0c74409774333820ef18 wp-block-paragraph\"><strong><mark class=\"has-inline-color has-teal-500-color\">Antes de prescribir Bridion\u00ae, consulte la informaci\u00f3n para prescribir completa.<\/mark><\/strong><\/p>\n\n\n\n<nav class=\"wp-block-mconnect-theme-curated-content \">\n\t<ul class=\"is-grid-layout has-columns has-two-columns has-top-vertical-alignment\" >\n\t\t\n\t<li class=\"grid-item\">\n\t\t<article\n            class=\"content-item  is-display-media-style is-missing-media has-link\"        >\n\t\n    \n    <div class=\"content-item__content-container\">\n\t\t<div class=\"content-item__content-body\">\n\t\t\t\t\t\t\t\t\t\t<span\n\t\t\t\t\tclass=\"content-item__primary-tag\"\n\t\t\t\t\ttitle=\"This item has been tagged as: ANESTESIA\"\n\t\t\t\t>\n\t\t\t\t\tANESTESIA\t\t\t\t<\/span>\n\t\t\t\t\t\t<header class=\"content-item__header\">\n\t\t\t\t<span\n\t\t\t\t\tclass=\"content-item__content-type content-type \">\n\t\t\t\t\t<span class=\"content-type__icon\">\n                                            <\/span>\n\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t<h2 class=\"content-item__title\" data-enterprise-id=\"currentHeader\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/informacion-para-prescribir-bridion-wp-0607\/\"\n                            class=\"content-item__title-link\"\n                            target=\"_self\"\n                            rel=\"\"\n\t\t\t\t\t\t\t              >\n                            Informaci\u00f3n para prescribir Bridion\u00ae                        <\/a>\n\t\t\t\t\t\t\t\t\t<\/h2>\n\t\t\t\t\t\t\t<\/header>\n\t\t\t\t\t\t\t<p class=\"content-item__excerpt\">BRIDION\u00ae Soluci\u00f3n inyectable, 100 mg\/mL PC-MK8616-EMEA\/H\/C\/000885\/11\/0042092020<\/p>\n\t\t\t\n                                            <div class=\"content-item__content-meta badge-container\">                                                                                                <\/div>\n                \t\t<\/div>\n\t\t<div class=\"content-item__content-footer\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t<\/div>\n\n    <\/article>\n\t<\/li>\n\t\n\n\t<li class=\"grid-item\">\n\t\t<article\n            class=\"content-item  is-display-media-style is-missing-media has-link\"        >\n\t\n    \n    <div class=\"content-item__content-container\">\n\t\t<div class=\"content-item__content-body\">\n\t\t\t\t\t\t\t\t\t\t<span\n\t\t\t\t\tclass=\"content-item__primary-tag\"\n\t\t\t\t\ttitle=\"This item has been tagged as: ANESTESIA\"\n\t\t\t\t>\n\t\t\t\t\tANESTESIA\t\t\t\t<\/span>\n\t\t\t\t\t\t<header class=\"content-item__header\">\n\t\t\t\t<span\n\t\t\t\t\tclass=\"content-item__content-type content-type \">\n\t\t\t\t\t<span class=\"content-type__icon\">\n                                            <\/span>\n\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t<h2 class=\"content-item__title\" data-enterprise-id=\"currentHeader\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/informacion-de-seguridad-bridion-wp-0599\/\"\n                            class=\"content-item__title-link\"\n                            target=\"_self\"\n                            rel=\"\"\n\t\t\t\t\t\t\t              >\n                            Informaci\u00f3n Seleccionada de Seguridad Bridion\u00ae                        <\/a>\n\t\t\t\t\t\t\t\t\t<\/h2>\n\t\t\t\t\t\t\t<\/header>\n\t\t\t\t\t\t\t<p class=\"content-item__excerpt\">Informaci\u00f3n Seleccionada de Seguridad Bridion\u00ae soluci\u00f3n inyectable 100 mg\/ml Indicaciones terap\u00e9uticas Reversi\u00f3n del bloqueo neuromuscular inducido por rocuronio o vecuronio [\u2026]<\/p>\n\t\t\t\n                                            <div class=\"content-item__content-meta badge-container\">                                                                                                <\/div>\n                \t\t<\/div>\n\t\t<div class=\"content-item__content-footer\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t<\/div>\n\n    <\/article>\n\t<\/li>\n\t\n\t<\/ul>\n<\/nav>\n\n\n\n<h4 class=\"wp-block-heading  mhh-mcn-v1-heading mhh-mcn-v1-heading--0623b53330ecc0ff91683e46fe4db97d\"><strong>Video de mecanismo de acci\u00f3n<\/strong><\/h4>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--2cd0bfb6695777ecd4092aa1893cdb4b wp-block-paragraph\" dir=\"ltr\" lang=\"es-CO\"><em>Sugammadex&nbsp;<\/em>es una gamma ciclodextrina modificada, que act\u00faa como un agente vinculante relajante selectivo. Forma un complejo con los bloqueadores neuromusculares rocuronio o vecuronio en plasma y por tanto reduce la cantidad del bloqueador neuromuscular disponible para unirse a los receptores nicot\u00ednicos en la uni\u00f3n neuromuscular. Esto produce una reversi\u00f3n del bloqueo neuromuscular inducido por el rocuronio o el vecuronio<sup>1<\/sup>.<\/p>\n\n\n\n<div  class=\"inpsyde-brightcove__player\" style=\"position: relative\">\n\n    \n    <video-js class=\"video-js vjs-fluid\" data-embed=\"default\" data-player=\"default\" data-account=\"1905768940001\" data-video-id=\"6351236685112\" aria-label=\"Video\" controls poster-url=\"https:\/\/cf-images.us-east-1.prod.boltdns.net\/v1\/jit\/1905768940001\/a17a2ff9-1493-4a20-b299-91021b39e4d9\/main\/1280x720\/2m39s850ms\/match\/image.jpg\"><\/video-js>\n\n        <img\n        class=\"inpsyde-brightcove__poster\"\n        src=\"https:\/\/cf-images.us-east-1.prod.boltdns.net\/v1\/jit\/1905768940001\/a17a2ff9-1493-4a20-b299-91021b39e4d9\/main\/1280x720\/2m39s850ms\/match\/image.jpg\"\n        alt=\"\"\n        fetchpriority=\"high\"\n        decoding=\"async\"\n        aria-hidden=\"true\"\n    \/>\n    \n    \n    <script src=\"https:\/\/players.brightcove.net\/1905768940001\/default_default\/index.min.js\"><\/script>\n<\/div>\n\n\n<div class=\"wp-block-mconnect-theme-accordion accordion \" data-has-first-expanded=\"false\">\n\t\n\n<button class=\"wp-block-mconnect-theme-accordion-item__header accordion-header \" id=\"accordion-6adc9fdceeaf2\" aria-controls=\"accordion-content-accordion-6adc9fdceeaf2\" data-tracking-id=\"accordion__section-toggle\">\n\t<strong>INDICACIONES<\/strong><\/button>\n<div class=\"wp-block-mconnect-theme-accordion-item__content accordion-content sub__entry__content\" id=\"accordion-content-accordion-6adc9fdceeaf2\" aria-labelledby=\"accordion-6adc9fdceeaf2\">\n\t\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--cd68500a8e41f1705fd67e2e129d07ae wp-block-paragraph\">Bridion<strong>\u00ae<\/strong> est\u00e1 indicado para la reversi\u00f3n del bloqueo neuromuscular inducido por rocuronio o vecuronio en adultos<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--c51bdff8c4fe3088206e07f006d5d851 wp-block-paragraph\">Para la poblaci\u00f3n pedi\u00e1trica, solo se recomienda el uso de <em>sugammadex <\/em>en ni\u00f1os y adolescentes, de edades comprendidas entre 2 y 17 a\u00f1os, para la reversi\u00f3n de rutina del bloqueo inducido por el rocuronio<sup>1<\/sup>.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/caja-bridion.png?w=457\" alt=\"\" class=\"wp-image-84160\" width=\"300\" height=\"217\" srcset=\"https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/caja-bridion.png 457w, https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/caja-bridion.png?resize=300,217 300w, https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/caja-bridion.png?resize=320,231 320w, https:\/\/msdconecta.co.cr\/es\/wp-content\/uploads\/sites\/77\/2023\/08\/caja-bridion.png?resize=120,87 120w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8495bbacf3d09d5ee8340b6ce9d112e7 wp-block-paragraph\">Referencias:<br>1.&nbsp;<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/ipc-bridion-nueva-wp-0430\/\">BRIDION<\/a>, informaci\u00f3n para prescribir.<\/p>\n\n<\/div>\n\n\n\n<button class=\"wp-block-mconnect-theme-accordion-item__header accordion-header \" id=\"accordion-6adc9fdcef533\" aria-controls=\"accordion-content-accordion-6adc9fdcef533\" data-tracking-id=\"accordion__section-toggle\">\n\t<strong>D<\/strong>OSIS Y VIA DE ADMINISTRACION<\/button>\n<div class=\"wp-block-mconnect-theme-accordion-item__content accordion-content sub__entry__content\" id=\"accordion-content-accordion-6adc9fdcef533\" aria-labelledby=\"accordion-6adc9fdcef533\">\n\t\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--729215369155c76c639e45d10e8b9ac0 wp-block-paragraph\">La dosis recomendada de Bridion<strong>\u00ae<\/strong> depende del nivel del bloqueo neuromuscular a ser revertido<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--b45c87c5f9427c7a75a32679e9cf39c7 wp-block-paragraph\">En estudios cl\u00ednicos Bridion<strong>\u00ae<\/strong> solo se administr\u00f3 por v\u00eda intravenosa como una inyecci\u00f3n en bolo<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--23aa500ed00199b4feccb7cf855a6162 wp-block-paragraph\">Si el bloqueo neuromuscular se requiere antes de que el tiempo de espera haya pasado, debe de usarse un agente bloqueador neuromuscular no esteroideo<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--1471eb2c3107c5aacd41a3c5209b7fd2 wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8495bbacf3d09d5ee8340b6ce9d112e7 wp-block-paragraph\">Referencias:<br>1.&nbsp;<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/ipc-bridion-nueva-wp-0430\/\">BRIDION<\/a>, informaci\u00f3n para prescribir.<\/p>\n\n<\/div>\n\n\n\n<button class=\"wp-block-mconnect-theme-accordion-item__header accordion-header \" id=\"accordion-6adc9fdcefa88\" aria-controls=\"accordion-content-accordion-6adc9fdcefa88\" data-tracking-id=\"accordion__section-toggle\">\n\t<strong>ADVERTENCIAS<\/strong><\/button>\n<div class=\"wp-block-mconnect-theme-accordion-item__content accordion-content sub__entry__content\" id=\"accordion-content-accordion-6adc9fdcefa88\" aria-labelledby=\"accordion-6adc9fdcefa88\">\n\t\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--6f7481d9e59105a4ec2601d043253271 wp-block-paragraph\">El soporte ventilatorio es obligatorio para los pacientes hasta que la respiraci\u00f3n espont\u00e1nea sea restablecida adecuadamente enseguida de la reversi\u00f3n del bloqueo neuromuscular. Aun si la recuperaci\u00f3n del bloqueo neuromuscular es completa, el uso de otros medicamentos en el periodo peri y post operatorio podr\u00edan deprimir la funci\u00f3n respiratoria y por lo tanto podr\u00eda requerirse de soporte ventilatorio<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--1471eb2c3107c5aacd41a3c5209b7fd2 wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8495bbacf3d09d5ee8340b6ce9d112e7 wp-block-paragraph\">Referencias:<br>1.&nbsp;<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/ipc-bridion-nueva-wp-0430\/\">BRIDION<\/a>, informaci\u00f3n para prescribir.<\/p>\n\n<\/div>\n\n\n\n<button class=\"wp-block-mconnect-theme-accordion-item__header accordion-header \" id=\"accordion-6adc9fdcf01d6\" aria-controls=\"accordion-content-accordion-6adc9fdcf01d6\" data-tracking-id=\"accordion__section-toggle\">\n\t<strong>P<\/strong>RECAUCIONES GENERALES<\/button>\n<div class=\"wp-block-mconnect-theme-accordion-item__content accordion-content sub__entry__content\" id=\"accordion-content-accordion-6adc9fdcf01d6\" aria-labelledby=\"accordion-6adc9fdcf01d6\">\n\t\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8f688664b1bffb8b9ee9d69f00df537f wp-block-paragraph\">El uso de sugammadex en pacientes con insuficiencia renal severa (incluyendo pacientes que requieren de di\u00e1lisis (CrCl &lt; 30 ml\/min) no est\u00e1 recomendado. Estudios en pacientes con insuficiencia hep\u00e1tica severa deben ser tratados con extrema precauci\u00f3n<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--38a5cf6568410006efa2204a0901d8d9 wp-block-paragraph\"><mark class=\"has-inline-color has-black-color\">Bridion\u00ae<\/mark> no ha sido investigado en pacientes que recibieron rocuronio o vecuronio estando en la UCI (unidad de cuidados intensivos)<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--1471eb2c3107c5aacd41a3c5209b7fd2 wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8495bbacf3d09d5ee8340b6ce9d112e7 wp-block-paragraph\">Referencias:<br>1.&nbsp;<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/ipc-bridion-nueva-wp-0430\/\">BRIDION<\/a>, informaci\u00f3n para prescribir.<\/p>\n\n<\/div>\n\n\n\n<button class=\"wp-block-mconnect-theme-accordion-item__header accordion-header \" id=\"accordion-6adc9fdcf0a6b\" aria-controls=\"accordion-content-accordion-6adc9fdcf0a6b\" data-tracking-id=\"accordion__section-toggle\">\n\t<strong>E<\/strong>MBARAZO Y LACTANCIA<\/button>\n<div class=\"wp-block-mconnect-theme-accordion-item__content accordion-content sub__entry__content\" id=\"accordion-content-accordion-6adc9fdcf0a6b\" aria-labelledby=\"accordion-6adc9fdcf0a6b\">\n\t\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--f683ab76536141c4a4268c846a508fdb wp-block-paragraph\">Embarazo<br>No existen datos cl\u00ednicos sobre la exposici\u00f3n de embarazadas a sugammadex.<br>Los estudios en animales no sugieren efectos perjudiciales directos ni indirectos sobre el embarazo, desarrollo embriofetal, parto o desarrollo posnatal.<br>Se debe actuar con precauci\u00f3n cuando se administre sugammadex a mujeres embarazadas<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--91d0e391407a67de3f45b7fb538c022f wp-block-paragraph\">Lactancia<br>Se desconoce si sugammadex se excreta en la leche materna humana. En estudios en animales se ha observado que sugammadex se excreta en la leche materna. La absorci\u00f3n oral de ciclodextrinas es por lo general baja y no se prev\u00e9 que tenga efecto sobre el lactante tras la administraci\u00f3n de una dosis \u00fanica a la mujer durante el periodo de lactancia.<br>Se debe decidir si es necesario interrumpir la lactancia o interrumpir el tratamiento, tras considerar el beneficio de la lactancia para el ni\u00f1o y el beneficio del tratamiento para la madre<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--c9d8c08f7b38f056b129e861890714ce wp-block-paragraph\">Fertilidad<br>No se han investigado los efectos de sugammadex en la fertilidad humana. Estudios en animales para evaluar la fertilidad no muestran efectos nocivos<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--1471eb2c3107c5aacd41a3c5209b7fd2 wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8495bbacf3d09d5ee8340b6ce9d112e7 wp-block-paragraph\">Referencias:<br>1.&nbsp;<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/ipc-bridion-nueva-wp-0430\/\">BRIDION<\/a>, informaci\u00f3n para prescribir.<\/p>\n\n<\/div>\n\n\n\n<button class=\"wp-block-mconnect-theme-accordion-item__header accordion-header \" id=\"accordion-6adc9fdcf1032\" aria-controls=\"accordion-content-accordion-6adc9fdcf1032\" data-tracking-id=\"accordion__section-toggle\">\n\t<strong>USO EN POBLACIONES ESPECIFICAS<\/strong><\/button>\n<div class=\"wp-block-mconnect-theme-accordion-item__content accordion-content sub__entry__content\" id=\"accordion-content-accordion-6adc9fdcf1032\" aria-labelledby=\"accordion-6adc9fdcf1032\">\n\t\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--43dc887e2337870c730eb52451f780de wp-block-paragraph\">Aun cuando los tiempos de recuperaci\u00f3n en los adultos mayores tienden a ser m\u00e1s lentos, debe de seguirse la recomendaci\u00f3n de la misma dosis que para los adultos<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--1471eb2c3107c5aacd41a3c5209b7fd2 wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8495bbacf3d09d5ee8340b6ce9d112e7 wp-block-paragraph\">Referencias:<br>1.&nbsp;<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/ipc-bridion-nueva-wp-0430\/\">BRIDION<\/a>, informaci\u00f3n para prescribir.<\/p>\n\n<\/div>\n\n\n\n<button class=\"wp-block-mconnect-theme-accordion-item__header accordion-header \" id=\"accordion-6adc9fdcf17e5\" aria-controls=\"accordion-content-accordion-6adc9fdcf17e5\" data-tracking-id=\"accordion__section-toggle\">\n\t<strong>INTERACCIONES CON OTROS MEDICAMENTOS<\/strong><\/button>\n<div class=\"wp-block-mconnect-theme-accordion-item__content accordion-content sub__entry__content\" id=\"accordion-content-accordion-6adc9fdcf17e5\" aria-labelledby=\"accordion-6adc9fdcf17e5\">\n\t\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--011adb91305a06536803b434335f79be wp-block-paragraph\">Un estudio en voluntarios demostr\u00f3 una prolongaci\u00f3n leve (11% a 22%) y transitoria (&lt;\/=30 minutos) de la TP (tiempo de protrombina) \/ TTPa (tiempo de tromboplastina parcial activada) con <mark class=\"has-inline-color has-black-color\">Bridion\u00ae<\/mark>. Con base en los datos cl\u00ednicos (n=1738) no hubo ning\u00fan efecto cl\u00ednicamente relevante de BRIDION solo o en combinaci\u00f3n con anticoagulantes sobre la incidencia de complicaciones hemorr\u00e1gicas peri o postoperatorias. <\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--2491ca0b560b44b744f5a8901bd49ee4 wp-block-paragraph\">Puesto que no existe informaci\u00f3n sobre el uso de Bridion<strong>\u00ae<\/strong> en pacientes con coagulopat\u00edas conocidas, los par\u00e1metros de coagulaci\u00f3n deben ser cuidadosamente monitoreados seg\u00fan la pr\u00e1ctica cl\u00ednica habitual. Aunque los estudios formales de interacci\u00f3n no se han realizado, no se observaron interacciones medicamentosas en estudios cl\u00ednicos<sup>1<\/sup>. Los datos precl\u00ednicos sugieren que las toremifeno, \u00e1cido fus\u00eddico y los anticonceptivos hormonales<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--1471eb2c3107c5aacd41a3c5209b7fd2 wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8495bbacf3d09d5ee8340b6ce9d112e7 wp-block-paragraph\">Referencias:<br>1.&nbsp;<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/ipc-bridion-nueva-wp-0430\/\">BRIDION<\/a>, informaci\u00f3n para prescribir.<\/p>\n\n<\/div>\n\n\n\n<button class=\"wp-block-mconnect-theme-accordion-item__header accordion-header \" id=\"accordion-6adc9fdcf1f79\" aria-controls=\"accordion-content-accordion-6adc9fdcf1f79\" data-tracking-id=\"accordion__section-toggle\">\n\t<strong>REACCIONES SECUNDARIAS Y ADVERSAS<\/strong><\/button>\n<div class=\"wp-block-mconnect-theme-accordion-item__content accordion-content sub__entry__content\" id=\"accordion-content-accordion-6adc9fdcf1f79\" aria-labelledby=\"accordion-6adc9fdcf1f79\">\n\t\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--aaf6a0822483e34c02e22898ac031434 wp-block-paragraph\">Las reacciones adversas m\u00e1s frecuentes fueron las complicaciones anest\u00e9sicas (por ejemplo, el movimiento, tos, hacer muecas, o succi\u00f3n en el tubo endotraqueal).<br>Las reacciones de hipersensibilidad se han producido en algunos pacientes y voluntarios. Estas reacciones var\u00edan desde reacciones cut\u00e1neas aisladas (enrojecimiento, urticaria, erupci\u00f3n eritematosa) a las reacciones sist\u00e9micas graves (por ejemplo, anafilaxis, shock anafil\u00e1ctico) y han ocurrido en pacientes sin exposici\u00f3n previa a <mark class=\"has-inline-color has-black-color\">Bridion\u00ae<\/mark><sup>1<\/sup>.<br>Como en todos los pacientes con antecedentes de complicaciones pulmonares, se debe tener en cuenta la posible ocurrencia de broncoespasmo<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--1471eb2c3107c5aacd41a3c5209b7fd2 wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"mhh-mcn-v1-paragraph mhh-mcn-v1-paragraph--8495bbacf3d09d5ee8340b6ce9d112e7 wp-block-paragraph\">Referencias:<br>1.&nbsp;<a href=\"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/anestesia\/ipc-bridion-nueva-wp-0430\/\">BRIDION<\/a>, informaci\u00f3n para prescribir.<\/p>\n\n<\/div>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Antes de prescribir Bridion\u00ae, consulte la informaci\u00f3n para prescribir completa. Video de mecanismo de acci\u00f3n Sugammadex&nbsp;es una gamma ciclodextrina modificada, [&hellip;]<\/p>\n","protected":false},"author":57544,"featured_media":0,"parent":0,"menu_order":6,"template":"","meta":{"_mhh_mcn_text_direction":"","_mhh_mcn_language":"","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":true,"isSticky":true},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"product_resource":[],"related_products":"","fact_sheet":null,"scientific_title":"","job_code":"","banner":null,"primary_logo":null,"secondary_logo":null,"icon":null,"primary_tag":0,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","mconnectIsArchiveTemplate":false,"mconnectArchiveFiltersDisabled":false,"mconnectArchiveLockAllPresetFilters":false,"mconnectArchiveHidePageSubmenu":false,"mconnectArchiveShowParentPageOnly":false,"mconnectArchiveDefaultOrder":"DESC","mconnectArchiveDefaultOrderBy":"date","mconnectArchivePostsPerPage":12,"mconnectArchivePostTypes":[],"mconnectArchiveAllowFilterBy":["category","tx-content-type","tx-product","tx-pathology","tx-active-ingredient","tx-therapeutic-area"],"mconnectArchiveTaxonomyOrder":[],"mconnectArchiveFilterSorting":["is_keyword"],"mconnectArchiveContentItemStyle":{"showExcerpt":true,"showImage":true,"showIcon":false,"showPrimaryTag":true,"showBorder":false,"showDates":false,"showCta":true,"isCard":false,"hasBackground":false,"showMetadata":true},"mconnectArchiveLayout":{"type":"list","hasFeatured":false},"mconnectDynamicTaxonomyEntities":[],"mconnectArchiveTerms_category":[],"mconnectArchiveAllowTerms_category":[],"mconnectArchiveTerms_tx-content-type":[],"mconnectArchiveAllowTerms_tx-content-type":[],"mconnectArchiveTerms_tx-product":[],"mconnectArchiveAllowTerms_tx-product":[],"mconnectArchiveTerms_tx-pathology":[],"mconnectArchiveAllowTerms_tx-pathology":[],"mconnectArchiveTerms_tx-active-ingredient":[],"mconnectArchiveAllowTerms_tx-active-ingredient":[],"mconnectArchiveTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_dynamic-taxonomy":[],"mconnectArchiveLegacyDefaultTermsApplied":false,"mconnectContentUpdatesPerPage":10,"mconnectContentUpdatesViewMoreUrl":"","mconnectContentUpdatesTerms_tx-content-type":[],"mconnectContentUpdatesTerms_tx-product":[],"mconnectContentUpdatesTerms_tx-pathology":[],"mconnectContentUpdatesTerms_tx-active-ingredient":[],"mconnectContentUpdatesTerms_tx-therapeutic-area":[],"sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[],"tags":[],"ga4_page_audience":[1187],"ga4_page_birn_id":[],"ga4_page_branding":[],"ga4_page_businessunit":[],"ga4_page_campaign":[],"ga4_page_content_purpose":[],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[],"ga4_page_product":[],"ga4_page_region":[921],"ga4_page_therapeuticarea":[],"tx-therapeutic-area":[],"tx-product":[],"tx-pathology":[],"tx-content-type":[],"tx-active-ingredient":[],"mhh-area-of-interest":[],"access":[],"user_status":[5,4,6],"user_role":[],"class_list":["post-84158","product","type-product","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bridion - MConnect Cenca Spanish<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/msdconecta.co.cr\/es\/products\/bridion-wp-0695\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bridion - MConnect Cenca Spanish\" \/>\n<meta property=\"og:description\" content=\"Antes de prescribir Bridion\u00ae, consulte la informaci\u00f3n para prescribir completa. 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