{"id":85900,"date":"2023-10-20T13:54:27","date_gmt":"2023-10-20T13:54:27","guid":{"rendered":"https:\/\/msdconecta.co.cr\/es\/?post_type=therapeutic-area&p=85900"},"modified":"2023-10-31T19:10:54","modified_gmt":"2023-10-31T19:10:54","slug":"dosis-y-administracion-januvia-wp-0516","status":"publish","type":"therapeutic-area","link":"https:\/\/msdconecta.co.cr\/es\/therapeutic-areas\/diabetes-2023-wp-0512\/januvia-wp-0521\/dosis-y-administracion-januvia-wp-0516\/","title":{"rendered":"Dosis y administraci\u00f3n Januvia"},"content":{"rendered":"
\n \"\"\n\n <\/figure>\n\n\n\n

Dosis y administraci\u00f3n<\/strong><\/strong><\/strong><\/h2>\n\n\n\n

La dosis recomendada de JANUVIA es de 100 mg una vez al d\u00eda como monoterapia o en tratamiento combinado con metformina, una sulfonilurea, insulina (con o sin metformina) o, con un agonista del PPARg (por ejemplo, la tiazolidinediona), metformina m\u00e1s una sulfonilurea, o metformina m\u00e1s un agonista del PPARg. JANUVIA se puede tomar con o sin alimentos.<\/p>\n\n\n\n

Cuando se usa JANUVIA en combinaci\u00f3n con una sulfonilurea o con insulina, se debe considerar emplear una dosis m\u00e1s baja de la sulfonilurea o de la insulina para reducir el riesgo de hipoglucemia inducida por sulfonilurea o insulina. (Ver PRECAUCIONES\/ADVERTENCIAS, Hipoglucemia en combinaci\u00f3n con una sulfonilurea o con insulina.)<\/p>\n\n\n\n

Pacientes con deterioro renal
Debido a que existe un ajuste de dosificaci\u00f3n en base a la funci\u00f3n renal, se recomienda la evaluaci\u00f3n de la funci\u00f3n renal antes de iniciar JANUVIA y peri\u00f3dicamente despu\u00e9s de ello.<\/p>\n\n\n\n

En los pacientes con deterioro renal leve (tasa de filtraci\u00f3n glomerular estimada (eGFR) \u226560 ml\/min\/1.73m2 a < 90 mL\/min\/1.73 m2) no es necesario realizar ajustes en la dosis de JANUVIA.<\/p>\n\n\n\n

Para pacientes con deterioro renal moderado (eGFR \u2265 45 mL\/min\/1.73 m2 a < 60 mL\/min\/1.73 m2), no es necesario realizar ajustes en la dosis de JANUVIA.<\/p>\n\n\n\n

En los pacientes con deterioro renal moderado (eGFR \u226530 mL\/min\/1.73 m2 a <45 ml\/min\/1.73 m2) la dosis de JANUVIA es de 50 mg una vez al d\u00eda.<\/p>\n\n\n\n

En los pacientes con deterioro renal severo (eGFR \u226515 mL\/min\/1.73 m2 a <30 mL\/min\/1.73 m2) o con enfermedad renal terminal (ERT) (eGFR < 15 mL\/min\/1.73 m2) incluyendo a aquellos que necesitan hemodi\u00e1lisis o di\u00e1lisis peritoneal, la dosis de JANUVIA es de 25 mg una vez al d\u00eda. JANUVIA se puede administrar independientemente de la hora de la di\u00e1lisis.<\/p>\n\n\n\n

Lo invitamos a que visite<\/strong><\/strong><\/strong><\/h2>\n\n\n
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<\/div>\n\n\n\n

Informaci\u00f3n sobre la diabetes, vida sana y consejos para el bienestar<\/strong><\/p>\n\n\n

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\n \n Ver m\u00e1s<\/span>\n <\/a><\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n\n
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Formaci\u00f3n y educaci\u00f3n m\u00e9dica continuada<\/strong><\/p>\n\n\n

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\n \n Ver m\u00e1s<\/span>\n <\/a><\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n\n<\/div>\n\n <\/div>\n\n <\/div>\n","protected":false},"excerpt":{"rendered":"

Dosis y administraci\u00f3n La dosis recomendada de JANUVIA es de 100 mg una vez al d\u00eda como monoterapia o en […]<\/p>\n","protected":false},"author":61360,"featured_media":0,"parent":86029,"menu_order":2,"template":"","meta":{"_mhh_mcn_text_direction":"","_mhh_mcn_language":"","_mhh_mcn_left_sidebar_settings":{"entityId":0},"_mhh_mcn_sidebar_settings":{"entityId":0},"mhh_mcn_side_navigation_style":{"fontSize":{"l":"","m":"","s":""},"lineHeight":{"l":1.5,"m":1.5,"s":1.5},"itemColor":"","hoverItemColor":"","currentItemColor":"","borderItemColor":"","backgroundItemHoverColor":"","themeColor":""},"_mhh_mcn_child_page_navigation":{"isActive":true,"isSticky":true},"hide_header":false,"show_top_bar":false,"hide_footer":false,"full_width_layout":false,"therapeutic_area_resource":[],"related_products":"","job_code":"","banner":null,"icon":null,"primary_tag":220,"editor_notices":[],"mconnectHideShareThis":false,"footnotes":"","mconnectIsArchiveTemplate":false,"mconnectArchiveFiltersDisabled":false,"mconnectArchiveLockAllPresetFilters":false,"mconnectArchiveHidePageSubmenu":false,"mconnectArchiveShowParentPageOnly":false,"mconnectArchiveDefaultOrder":"DESC","mconnectArchiveDefaultOrderBy":"date","mconnectArchivePostsPerPage":12,"mconnectArchivePostTypes":[],"mconnectArchiveAllowFilterBy":["category","tx-content-type","tx-product","tx-pathology","tx-active-ingredient","tx-therapeutic-area"],"mconnectArchiveFilterSorting":["is_keyword"],"mconnectArchiveContentItemStyle":{"showExcerpt":true,"showImage":true,"showIcon":false,"showPrimaryTag":true,"showBorder":false,"showDates":false,"showCta":true,"isCard":false,"hasBackground":false,"showMetadata":true},"mconnectArchiveLayout":{"type":"list","hasFeatured":false},"mconnectDynamicTaxonomyEntities":[],"mconnectArchiveTerms_category":[],"mconnectArchiveAllowTerms_category":[],"mconnectArchiveTerms_tx-content-type":[],"mconnectArchiveAllowTerms_tx-content-type":[],"mconnectArchiveTerms_tx-product":[],"mconnectArchiveAllowTerms_tx-product":[],"mconnectArchiveTerms_tx-pathology":[],"mconnectArchiveAllowTerms_tx-pathology":[],"mconnectArchiveTerms_tx-active-ingredient":[],"mconnectArchiveAllowTerms_tx-active-ingredient":[],"mconnectArchiveTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_tx-therapeutic-area":[],"mconnectArchiveAllowTerms_dynamic-taxonomy":[],"mconnectArchiveLegacyDefaultTermsApplied":false,"mconnectContentUpdatesPerPage":10,"mconnectContentUpdatesViewMoreUrl":"","mconnectContentUpdatesTerms_tx-content-type":[],"mconnectContentUpdatesTerms_tx-product":[],"mconnectContentUpdatesTerms_tx-pathology":[],"mconnectContentUpdatesTerms_tx-active-ingredient":[],"mconnectContentUpdatesTerms_tx-therapeutic-area":[],"sidebar_toogle":0,"sidebar_toogle_notification_warning":true,"sidebar_toogle_notification_alert":true,"content_expiration_sidebar_date":"","content_expiration_sidebar_expired_post_status":"","content_expiration_sidebar_redirection":""},"categories":[],"tags":[220],"ga4_page_audience":[1187],"ga4_page_birn_id":[],"ga4_page_branding":[],"ga4_page_businessunit":[],"ga4_page_campaign":[],"ga4_page_content_purpose":[],"ga4_page_customer_journey_stage":[],"ga4_page_customer_specialty":[],"ga4_page_experience":[],"ga4_page_indication":[],"ga4_page_material_intent":[],"ga4_page_product":[],"ga4_page_region":[921],"ga4_page_therapeuticarea":[],"therapeutic-area-group":[],"tx-therapeutic-area":[221],"tx-product":[],"tx-pathology":[],"tx-content-type":[],"tx-active-ingredient":[],"mhh-area-of-interest":[],"access":[],"user_status":[],"user_role":[],"class_list":["post-85900","therapeutic-area","type-therapeutic-area","status-publish","hentry","tag-diabetes"],"yoast_head":"\nDosis 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